输液管理可改善败血症的预后

Sepsis is a life-threatening condition that occurs when the body damages its own organs while trying to fight an infection; it’s an infection response out of control and its impact is vast.  

Raising awareness and advancing patient care for sepsis remains critical. 艾弗·道格拉斯,M.D., Professor of Medicine at the University of Colorado and Chief of Pulmonary and Critical Care Medicine at Denver Health Medical Center, discusses how he is using the results of a recent clinical trial to help improve and personalize care for sepsis patients.

研究结果 Fluid Response Evaluation in Sepsis Hypotension and Shock (FRESH) clinical trial showed that personalized intravenous (IV) fluid management decisions may help improve patient outcomes. The study's objective was to assess the mean difference in fluid balance at 72 hours or ICU discharge, 先到先得, 以及相关的次要患者结果. One of the outcomes assessed was how patients with septic shock were impacted when their clinician performed a dynamic assessment of fluid responsiveness before administering any fluid.

Dr. Douglas, primary investigator of the FRESH study, shares his perspective: 

医疗专业人员的大头照

My strong sense is that the FRESH trial results will lead to future changes in usual resuscitation care for sepsis patients. The significant reductions in respiratory and 肾 organ failures were clinically meaningful. 同时继续研究这种方法, at my institution we have implemented routine dynamic fluid response measures from the very front door of the hospital to the emergency room (ER). We have trained our frontline providers in the ER and our sepsis response teams to quickly recognize organ failure hyperfusion related to sepsis and other causes and oversee dynamic fluid response-guided resuscitation. 这有助于优化早期护理过程, 但更重要的是, it creates a continuum of care into the intensive care unit (ICU) if a patient isn’t immediately stabilized.

Dr. 艾弗道格拉斯, Professor of Medicine at the University of Colorado and Chief of Pulmonary and Critical Care Medicine at Denver Health Medical Center

听听Dr. 道格拉斯对ladbrokes立博体育的新看法 在液体 播客 focused on how fluid management can help support improved patient care.

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